Table 3. Curcuma extract effects on cardiac parameters.

	Left & Right atrium		Ventriculum
	Negative Inotropic Activitya	Negative Chronotropic Activityb	Negative Inotropic Activityc
Curcuma extract	27 ± 1.3	39 ± 2.1	33 ± 1.9
Curcuma extract + atropine (1µM)	21 ± 2.0	33 ± 3.1	30 ± 0.9
Curcuma extract + DPCPX (1µM)	25 ± 1.1	36 ± 1.8	34 ± 1.4

^a Activity: decrease in developed tension on isolated spontaneously beating mice atria at 1mg/ml, expressed as percent changes from the control (n = 4–6). ^b Activity: decrease on atrial rate in spontaneously beating isolated mice atria at 1 mg/ml, expressed as percent changes from the control (n = 6–8). Pretreatment heart rate ranged from 300 to 350 beats per min. ^c Activity: decrease in developed tension on isolated mice ventricula muscle driven at 1 Hz at 1mg/ml, expressed as percent changes from the control (n = 4–6).