Table 4. Univariate and multivariate analysis to identify independent risk factors for LRE development.

Variables	Univariate	Multivariate
(at 3 months after Kasai)	P	P	Hazard ratio	95% confidence interval
LSM value (kPa)	<0.001	0.018	1.258	1.032–1.522
AST (IU/L)	0.001	0.369	1.006
ALT (IU/L)	0.039	0.323	0.992
Albumin (g/dL)	<0.001	0.538	0.529
Total bilirubin (mg/dL)	<0.001	0.054	1.635
Direct bilirubin (mg/dL)	<0.001
ALP (IU/L)	0.063
Platelet count(109/L)	0.139

LRE, liver related events; LSM, liver stiffness measurement; AST, aspartate aminotransferase; ALT, alanine aminotransferase; GGT, gamma glutamyl transpeptidase; ALP, alkaline phosphatase.