Table 1. Characteristics of the SELE gene A561C polymorphism genotype distributions in studies included in this meta-analysis.

First author	Year	Country	Ethnicity	Case	N	Genotypes AA/AC/CC		F	% of male		Mean age		P a
						Case	Control		Case	Control	Case	Control
Wenzel [32]	1997	Germany	Caucasian	CHD	216	79/33/1	87/14/2	0.087	88	90	42b	38b	0.13
Ye [33]	1999	America	Caucasian	CAD	153	52/28/2	56/15/0	0.106	57	45	Na	Na	0.32
Lin [34]	2001	China	Asian	CAD	177	71/20/1	77/8/0	0.047	73	65	63.9	60.2	0.65
Yoshida [22]	2003	Japan	Asian	MI	462	118/17/0	305/22/0	0.034	76	70	57.7	47.6	0.53
Luo [37]	2003	China	Asian	CHD	190	74/17/2	87/10/0	0.052	87	89	54.0	56.0	0.59
Li [39] c	2004	China	Asian	MI	388	170/28/0	177/13/0	0.034	76	76	66.1	67.8	0.63
Li [39] c	2004	China	Asian	MI	372	162/25/0	173/12/0	0.032	79	80	56.7	54.7	0.65
Wei [40]	2004	China	Asian	AP	280	119/16/0	138/7/0	0.024	64	64	61.7	60.5	0.77
Huang [36]	2004	China	Asian	AP	315	132/23/0	149/11/0	0.034	72	72	61.7	60.7	0.65
Abu-Amero [23]	2006	Saudi Arabia	Caucasian	CAD	793	451/92/13	208/28/1	0.063	71	44	50.0	50.0	0.96
Hu [41]	2006	China	Asian	CHD	410	162/33/2	202/11/0	0.026	57	59	62.3	61.5	0.70
Jiang [42]	2006	China	Asian	CHD	289	89/52/4	130/14/0	0.049	66	61	61.7	59.7	0.54
Hamid [43]	2007	Egypt	Caucasian	CAD	50	23/5/2	18/2/0	0.05	80	80	45.7	47.8	0.81
Wei [44]	2007	China	Asian	AMI	368	147/20/1	182/16/2	0.05	61	60	64.0	63.0	0.03*
Ma [45] d	2008	China	Asian	CHD	204	85/22/1	87/9/0	0.047	100	100	65.4	66.1	0.63
Ma [45] d	2008	China	Asian	CHD	92	30/12/0	45/5/0	0.05	100	100	69.8	67.8	0.71
Zak [46]	2008	Poland	Caucasian	CAD	394	149/38/4	161/40/2	0.108	67	76	43.8	35.3	0.78
Zeng [47]	2008	China	Asian	CHD	410	196/23/1	182/8/0	0.021	62	62	65.0	63.0	0.77
Tripathi [49]	2009	India	Asian	CAD	660	273/56/0	294/37/0	0.056	79	74	57.1	53.2	0.28
Hong [48]	2009	China	Asian	CHD	82	53/13/0	14/2/0	0.063	Na	Na	Na	Na	0.79
Sakowicz [50]	2010	Poland	Caucasian	MI	298	116/41/5	102/29/5	0.143	83	47	40.9	54.3	0.12
Fang [51]	2011	China	Asian	ACSe	82	30/5/4	41/2/0	0.023	Na	Na	Na	Na	0.88
Motawi [24]	2012	Egypt	Caucasian	CAD	150	51/21/3	69/6/0	0.04	51	33	56.7	59.9	0.72

CHD: coronary heart disease, CAD: coronary artery disease, MI: myocardial infarction, AP: angina pectoris, AMI: acute myocardial infarction.

ACS: acute coronary syndrome, N: total number of subjects in each study, F: the C allele frequency in control, Na: not available. * P<0.05.

^a P for Hardy–Weinberg equilibrium in the control group.

^bOnly the median age of cases and controls was available from the original article.

^c/dOne study with different populations.

^eACS mainly included unstable angina pectoris, myocardial infarction, coronary death in the original article.