Table 2. Characteristics of the SELE gene G98T polymorphism genotype distributions in studies included in this meta-analysis.
First author | Year | Country | Ethnicity | Case | N | Genotypes GG/GT/TT | F | % of male | Mean age | P a | |||
Case | Control | Case | Control | Case | Control | ||||||||
Zheng [35] | 2001 | American | Caucasian | CAD | 101 | 31/18/2 | 40/10/0 | 0.1 | 54.9 | 42 | Na | Na | 0.43 |
Luo [37] | 2003 | China | Asian | CHD | 190 | 72/15/6 | 85/11/1 | 0.067 | 87.1 | 88.7 | 54.0 | 56.0 | 0.36 |
Li [38] | 2004 | China | Asian | CHD | 437 | 210/27/1 | 181/18/0 | 0.045 | 71.0 | 70.4 | 63.5 | 61.9 | 0.50 |
Ma [45] b | 2008 | China | Asian | CHD | 204 | 90/18/0 | 83/13/0 | 0.068 | 100.0 | 100.0 | 65.4 | 66.1 | 0.48 |
Ma [45] b | 2008 | China | Asian | CHD | 92 | 35/7/0 | 41/9/0 | 0.09 | 100.0 | 100.0 | 69.8 | 67.8 | 0.48 |
Zak [46] | 2008 | Poland | Caucasian | CAD | 394 | 150/37/4 | 164/37/2 | 0.101 | 66.5 | 75.9 | 43.8 | 35.3 | 0.96 |
Zeng [47] | 2008 | China | Asian | CHD | 410 | 187/33/0 | 174/16/0 | 0.042 | 61.8 | 62.1 | 65.0 | 63.0 | 0.55 |
Hong [48] | 2009 | China | Asian | CHD | 82 | 58/8/0 | 11/5/0 | 0.156 | Na | Na | Na | Na | 0.46 |
Zhang [52] | 2011 | China | Asian | CHD | 328 | 150/26/0 | 141/11/0 | 0.036 | 61.9 | 66.7 | 62.9 | 63.7 | 0.64 |
CHD: coronary heart disease, CAD: coronary artery disease, N: total number of subjects in each study, F: the T allele frequency in control.
Na: not available.
P for Hardy –Weinberg equilibrium in control group.
One study with different populations.