. 2013 Nov 18;8(11):e79301. doi: 10.1371/journal.pone.0079301

Table 3. Pooled measures on the relationship of the SELE gene A561C polymorphism with CAD.

Data	Population	Model	Before Sensitive Analysis				After Sensitive Analysis
			Pooled OR (95% CI)		I ²	P _h	Pooled OR (95% CI)		I ²	P _h
			FEM	REM	(%)		FEM	REM	(%)
All includedarticles	Overall	Dominant	2.12 (1.83–2.44)^**	2.23 (1.83–2.71)^**	39.6	0.028	1.81 (1.55–2.12)^**	1.80 (1.54–2.11)^**	0	0.687
		Codominant	2.03 (1.78–2.33)^**	2.14 (1.76–2.60)^**	43.9	0.013	1.73 (1.49–2.00)^**	1.71 (1.48–1.99)^**	0	0.645
	Asian	Dominant	2.49 (2.06–3.00)^**	2.48 (2.02–3.04)^**	12.3	0.312	2.08 (1.69–2.57)^**	2.07 (1.67–2.11)^**	0	0.966
		Codominant	2.40 (2.01–2.87)^**	2.38 (1.93–2.92)^**	18.5	0.242	1.99 (1.62–2.43)^**	1.97 (1.61–2.42)^**	0	0.965
	Caucasian	Dominant	1.66 (1.32–2.08)^**	1.78 (1.25–2.54)^**	51.0	0.057	1.52 (1.20–1.93)^**	1.53(1.17–2.00)^**	15.5	0.314
		Codominant	1.62 (1.32–2.00)^**	1.74 (1.24–2.44)^**	55.0	0.038	1.47 (1.18–2.00)^**	1.47 (1.14–1.90)^**	24.0	0.262
Excluded forDHWE	Overall	Dominant	2.15 (1.86–2.50)^**	2.28 (1.86–2.80)^**	40.3	0.027	1.84 (1.56–2.16)^**	1.83 (1.55–2.15)^**	0	0.653
		Codominant	2.06 (1.80–2.37)^**	2.19 (1.78–2.68)^**	45.4	0.011	1.74 (1.49–2.03)^**	1.73 (1.48–2.01)^**	0	0.588
	Asian	Dominant	2.89 (2.14–3.16)^**	2.57 (2.10–3.14)^**	3.6	0.412	2.16 (1.73–2.70)^**	2.15(1.72–2.69)^**	0	0.984
		Codominant	2.50(2.07–3.01)^**	2.47 (2.00–3.04)^**	14.3	0.293	2.05 (1.65–2.54)^**	2.04 (1.64–2.52)^**	0	0.973
	Caucasian	Dominant	1.66 (1.32–2.08)^**	1.78 (1.25–2.54)^**	51.0	0.057	1.52 (1.20–1.93)^**	1.53 (1.17–2.00)^**	15.5	0.314
		Codominant	1.62 (1.32–2.00)^**	1.74 (1.24–2.44)^**	55.0	0.038	1.47 (1.18–1.82)^**	1.47 (1.14–1.90)^**	24.0	0.262

Dominant model: CC + AC versus AA; Codominant model: C versus A.

FEM: fixed effect model, REM: random effect model, DHWE: deviated from Hardy–Weinberg equilibrium.

^**

P<0.01.

P _h: P value of Q-test for heterogeneity test.