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. 2013 Nov 18;8(11):e80486. doi: 10.1371/journal.pone.0080486

Table 3. Main effect and interaction effect of DM and inflammation (as assessed from hsCRP or SA) on all-cause or cardiovascular death.

All-cause death
Cardiovascular death
adjusted HR (95% CI)      P  adjusted HR (95% CI)      P
DM (non-DM as reference) 1.639(1.350-1.989) <0.001 1.984(1.441-2.732) <0.001
hsCRP (every 10 mg/L increase) 1.062(1.046-1.077) <0.001 1.065(1.045-1.086) <0.001
interaction effect of DM and hsCRP 1.005(1.001-1.009) 0.013 1.005(1.000-1.011) 0.05
DM (non-DM as reference) 2.295(1.104-3.489) 0.032 2.608(1.271-3.946) 0.036
SA (every 1 g/L increase) 0.887(0.856-0.919) <0.001 0.885(0.866-0.904) <0.001
interaction effect of DM and SA 1.044(1.012-1.077) 0.007 1.047(1.001-1.093) 0.021

DM: diabetes mellitus; hsCRP: high-sensitive C-reactive protein; SA: serum albumin