Table 4. Activity breakdown of Rtt109-Vps75 HTS.

	Number of compounds
Percent inhibition (%)a	HTS1 (no detergent)	HTS2 (detergent)	Cumulative
>95	113	46	159
90–95	24	17	41
75–90	89	39	128
50–75	287	149	436
40–50	238	148	386
30–40	575	302	877
3σb	667 (0.80%)	920 (0.64%)	1587c (0.70%)

^a = compounds tested at 10 µM final reaction concentrations;

^b = 3σ corresponds to 42.9 and 26.4 percent inhibition for HTS1 and HTS2, respectively;

^c = combined from the separate HTS1 and HTS2 analyses.