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. 2013 Nov 18;8(11):e81253. doi: 10.1371/journal.pone.0081253

Figure 1. Determining the toxaphene IC20 for functional profiling.

Figure 1

(A) The structure of two chlorinated congeners present in the toxaphene technical mixture. (B) Representative growth curves in YPD media for the BY4743 wild-type strain treated with toxaphene. For clarity, only the 250, 550, and 1000μM toxaphene doses are shown, although additional curves were performed at 400, 700, and 850μM. (C) The area under the curve (AUC) was calculated at each dose for three independent experiments, expressed as the mean and SE, and plotted as a percentage of the untreated control. The toxaphene IC20 was determined to be 640μM, as indicated by the dashed lines.