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. 2013 Nov 18;8(11):e81253. doi: 10.1371/journal.pone.0081253

Figure 7. Toxaphene does not inhibit transcription elongation.

Figure 7

(A) GLAM-ratios are not altered upon toxaphene treatment. The acid phosphatase activity of long (PHO5-lacZ or PHO5-LAC4) versus short (PHO5) transcriptional units was measured and the means and SE are shown for three independent experiments. The mft1Δ strain was used as a positive control. (B) Toxaphene does not affect RNA processivity. Levels of RNA polymerase II bound to different regions of a long gene were measured by chromatin immunoprecipitation.