Table 1. The IC50 values of compounds 19 (as reference), 11 and 8a-8d against human heparanase.
Compound | IC50 (n=3) |
---|---|
OGT2115, 20 | 10±2 μM |
11 | > 10 mM |
8a | 1.2±0.3 mM |
8b | 0.8±0.2 mM |
8c | > 10 mM |
8d | 0.8±0.2 mM |
The values are mean of three readings ± standard error.