µ
|
Spring constant |
30 N Cell diameter-1
|
30 N Cell diameter-1
|
45 N Cell diameter-1
|
η
|
Drag coefficient |
1 N hours Cell diameter-1
|
1 N hours Cell diameter-1
|
1 N hours Cell diameter-1
|
s
|
Equilibrium spring rest length |
1 Cell diameter |
1 Cell diameter |
1 Cell diameter |
β
|
Basement membrane force parameter |
-- |
-- |
12 N Cell diameter-1
|
κs
|
Spontaneous curvature for crypt base |
-- |
-- |
0.3 Cell diameter-1
|
AT
|
Threshold area for cell division |
-- |
-- |
0.5 Cell diameter2
|
A0
|
Equilibrium area of a cell |
Cell diameter2
|
Cell diameter2
|
Cell diameter2
|
ΔT
|
Timestep |
0.005 hours |
0.005 hours |
0.0042 hours |
HT
|
Threshold height for cell sloughing |
12 Cell diameter |
12 Cell diameter |
0.9 of total crypt length (variable) |
WT
|
Wnt threshold that defines the proliferative compartment |
0.65 |
0.65 |
0.65 |