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. 2013 Nov 8;8(11):e78267. doi: 10.1371/journal.pone.0078267

Figure 4. RAGEΔICD affects S100B induced cellular migration.

Figure 4

A–B. C6 glioma cells expressing RAGE, RAGEΔICD, or empty vector (mock) were assessed for S100B induced migration using chemotaxis assays. Cells were seeded into the upper chamber of a Boyden transwell filters and allowed to migrate toward 5 ug/ml S100B stimulant for 24 hours. A. Representative images are shown. B. quantitation of relative cell migration normalized to mock transfected cells. Data are means ± SEM from three independent experiments, where *, significant differences (P = 0.03) between groups; and #, p = 0.006.