Table 1. Modulation of the expression of a series of phase I metabolization enzymes in HepG2 and A549 cells exposed for 14[a]P from 0.2 to 5 µM.

	HepG2			A549
B[a]P (µM)	CYP1A2	CYP3A4	EPH	CYP1A2	CYP3A4	EPH
0.2	3.25±0.34 *	1.61±0.15	0.86±0.10	2.41±1.34	1.21±0.10	0.68±0.34
2	3.77±0.63 *	1.14±0.11	0.77±0.22	2.64±0.78	1.29±0.05	0.77±0.22
5	4.79±1.45 *	2.18±0.82	1.05±0.04	2.23±0.85	2.75±0.48 *	0.80±0.19

(Statistically significant (p<0.05) with respect to (*) DMSO control of the concerned cell line).