Table 3. Increase in EROD activitya measured in HepG2 and A549 cells exposed to B[a]P from 0.2 to 5 µM.
B[a]P (µM) | 0 | 0.2 | 2 | 5 |
A549 | 0.00±0.08 | 0.28±0.08 | 0.46±0.11 | 0.59±0.17 |
HepG2 | 0.00±0.05 | 0.30±0.11 | 3.49±0.61 | 7.25±0.45 |
Exposure time was 24 h for HepG2 and 48 h for A549.
a: expressed in pmol of product/min/mg of protein. The average background measured in untreated cells value was subtracted.