Fig. 2.

The absence of suppression of outgrowth of tumor clones from DLN of control tumor-bearing BALB/c mice by DLN from CD200KO or CD200R1KO mice. DLN cells from control mice (3/group) were cultured under limiting dilution conditions (from 2 × 10³ to 1 × 10⁵ cells/well) alone, or with a 5-fold excess of DLN cells from CD200KO or CD200R1KO mice (from 1 × 10⁴ to 5 × 10⁵) at each of the time points shown (day 15 post-initial tumor cell injection represents the day of surgical resection). Cells from CD200KO or CD200R1KO mice were also cloned alone at each time point (data to far right of Figure). All frequencies of tumor cells cloned were calculated based on the input numbers of cells from DLN of control mice only. *^,**p < 0.05 compared with day of surgery or day 14 post-surgery, respectively