Fig. 3.

Lung and liver metastases in control, CD200KO or CD200R1KO BALB/c mice receiving 5 × 10⁵ EMT6 tumor cells subcutaneously into the mammary fat pads, followed by surgical resection 15 days later, with subsequent immunization with EMT6 with CpG as adjuvant (a), no immunization (b), or immunization with CpG alone c) or CpG with irradiated 4T1 tumor cells (d). Six mice were used per group for sacrifice at each time point (numbers surviving shown at side of each bar). Data show mean ± SD for macroscopic tumor colonies/group; ns no survivors, nd not done