Fig. 3.

Reduction in average daily SIS. a LS mean (SEM) absolute change by age subgroup. p-Value is for the test of difference in the LS mean absolute change from baseline between G-GR age groups and their respective placebo groups based on the ANCOVA model that includes treatment and center factors, and baseline pain score as a covariate. b Forest plot for LS mean difference in SIS. ANCOVA analysis of covariance, G-GR gastroretentive gabapentin, LS least square, SEM standard error of the mean, SIS sleep interference score