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. 2013 Nov 19;7:216. doi: 10.3389/fnins.2013.00216

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Copyright © 2013 Tortorella, Rodrigo-Angulo, Núñez and Garzón.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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PnO electrical stimulation evoked a long-lasting inhibition of PeFLH neurons. (A) Electrical train stimulation of the PnO nucleus evoked a decrease in PeFLH neuronal activity for 5 s accompanied by a slight decrease in EEG slow waves. The stimulation train is indicated with open arrow. (B) The PnO-evoked inhibition was abolished by bicuculline (10 mM). (C) Plot of the mean firing rate calculated for the 10 s period before (black) and after (red) the PnO stimulation train in control animals (n = 14 cells) and 5 min after bicuculline application (n = 8 cells). The PnO-evoked inhibition was blocked by the GABA_A receptor antagonist. The asterisk indicates significant statistical differences (^**p < 0.01).