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. 2013 Nov 16;13:550. doi: 10.1186/1471-2407-13-550

Table 3.

Comparison of each US feature of 1449 thyroid nodules according to underlying echogenicity

 
Total
Malignant
Benign
  Heterogeneous echogenicity Homogeneous echogenicity P -value Heterogeneous echogenicity Homogeneous echogenicity P -value Heterogeneous echogenicity Homogeneous echogenicity P -value
Total number
317
1132
 
68
257
 
249
875
 
Echogenicity
 
 
0.078
 
 
0.174
 
 
0.068
  Hyper/isoechogenicity
125 (39.4)
525 (46.4)
 
3 (4.4)
28 (10.9)
 
122 (49.0)
497 (56.8)
 
  Hypoechogenicity
176 (55.5)
549 (48.5)
 
56 (82.4)
186 (72.4)
 
120 (48.2)
363 (41.5)
 
  Marked hypoechogenicity
16 (5.1)
58 (5.1)
 
9 (13.2)
43 (16.7)
 
7 (2.8)
15 (1.7)
 
Margin
 
 
0.005
 
 
0.314
 
 
<0.001
  Well circumscribed
203 (64.0)
818 (72.3)
 
12 (17.7)
60 (23.4)
 
191 (76.7)
758 (86.6)
 
  microlobulated or irregular
114 (36.0)
314 (27.7)
 
56 (82.4)
197 (76.7)
 
58 (23.3)
117 (13.4)
 
Calcifications
 
 
0.849
 
 
0.986
 
 
0.555
  Microcalcifications
42 (13.3)
141 (12.5)
 
29 (42.7)
108 (42.0)
 
13 (5.2)
33 (3.8)
 
  Macrocalcifications
39 (12.3)
151 (13.3)
 
9 (13.2)
36 (14.0)
 
30 (12.1)
115 (13.1)
 
  No calcifications
236 (74.5)
840 (74.2)
 
30 (44.1)
113 (44.0)
 
206 (82.7)
727 (83.1)
 
Shape
 
 
0.737
 
 
0.790
 
 
0.245
  Wider than tall
251 (79.2)
906 (80.0)
 
29 (42.7)
105 (40.9)
 
222 (89.2)
801 (91.5)
 
  Taller than wide 66 (20.8) 226 (20.0)   39 (57.4) 152 (59.1)   27 (10.8) 74 (8.5)