Table 2.
Association of HERC4 expression with patient’s clinicopathological features in 120 invasive ductal carcinoma
| Variables |
HERC4 staining |
|||
|---|---|---|---|---|
| Negative(%) | Positive(%) | Total | P value b | |
| Age(years) |
|
|
|
|
| ≤50a |
25(45.5) |
30(54.5) |
55 |
0.927 |
| >50 |
29(44.6) |
36(55.4) |
65 |
|
| pT status |
|
|
|
|
| T1 |
15(88.2) |
2(11.8) |
17 |
0.000 |
| T2 |
36(42.9) |
48(57.1) |
84 |
|
| T3 |
3(18.8) |
16(81.2) |
19 |
|
| Lymph node metastasis |
|
|
|
|
| Negative |
32(80) |
8(20) |
40 |
0.000 |
| Positive |
22(27.5) |
58(72.5) |
80 |
|
| Histology grade |
|
|
|
|
| I |
41(95.3) |
2(4.7) |
43 |
0.000 |
| II |
13(24.5) |
40(75.5) |
53 |
|
| III |
0(0) |
24(100) |
24 |
|
| Stage |
|
|
|
|
| I-II |
43(76.8) |
13(23.2) |
56 |
0.000 |
| III-IV |
11(17.2) |
53(82.8) |
64 |
|
| ER status |
|
|
|
|
| Negative |
25(43.1) |
33(56.9) |
58 |
0.686 |
| Positive |
29(46.8) |
33(53.2) |
62 |
|
| PR status |
|
|
|
|
| Negative |
31(50) |
31(50) |
62 |
0.255 |
| Positive |
23(39.7) |
35(60.3) |
58 |
|
| HER2 status |
|
|
|
|
| Negative |
15(42.9) |
20(57.1) |
35 |
0.762 |
| Positive |
39(45.9) |
46(54.1) |
85 |
|
| P53 status |
|
|
|
|
| Negative |
23(41.8) |
32(58.2) |
55 |
0.519 |
| Positive |
31(47.7) |
34(52.3) |
65 |
|
| Ki67 status |
|
|
|
|
| Negative |
15(38.5) |
24(61.5) |
39 |
0.318 |
| Positive | 39(48.1) | 42(51.9) | 81 | |
a Mean age.
b P value are from χ2-test.