Table 2.
Comparison of amino acid signatures in selected genes of avian and human strains to Egyptian H5N1 strains
| Gene | Residue | Avian1 | Human | Egyptian H5N1 | A/CK/Egypt/F10/2009 |
| PB2 | 475 | L214M1 | M839L3 | L52M2 | L |
| 588 | A203/T6/V6 | I835/V3/A2 | A53/T1 | A | |
| 613 | V212/A3 | T816/I16/A8/V1 | V54 | V | |
| 627 | E196/K19 | K838/R2/E1 | K48/E6 | K | |
| 674 | A204/S6/T2/G2/E1 | T836/A2/I2/P1 | A54 | A | |
| PB1 | 327 | R147/K3 | K766/R66 | R58 | R |
| 336 | V142/I8 | I773/V59 | V58 | V | |
| PA | 225 | S213C1 | C829S10 | S | S |
| 268 | L214 | I827K11 | L | L | |
| 356 | K212X1R1 | R827K11 | K | K | |
| 382 | E208D5V1 | D824E11V2N1 | E | E | |
| 404 | A214 | S828A9P1 | A | A | |
| 409 | S189N24I1 | N830S7I1 | S77N1 | S | |
| NP | 283 | L372/P1 | L7/P643 | L61 | L |
| 293 | R371/K2 | R28/K622 | R60/K1 | R | |
| 305 | R369/K4 | K636/R14 | R61 | R | |
| 313 | F371/I1/L1 | Y642/F8 | F61 | F | |
| 357 | Q368/K4/T1 | K44/R8/Q1 | Q61 | Q | |
| 372 | E357/D15/K1 | D630/E23 | E61 | E | |
| 422 | R373 | K630/R23 | R61 | R | |
| 442 | T372/A1 | A629/T23/R1 | T61 | T | |
| 455 | D373 | E630/D22/T1 | D60/E1 | D | |
| M1 | 115 | V856/I2/L1/G1 | I981/V9 | V88 | V |
| 121 | T840/A19/P1 | A988/T2 | T88 | T | |
| 137 | T859/A1/P1 | A974/T12 | T88 | T | |
| M2 | 11 | T434/I11/S2 | I911/T44 | T90 | T |
| 20 | S471/N13 | N926/S29 | S90 | S | |
| 57 | Y481/C1/H1 | H913/Y33/R2/Q1 | Y90 | Y | |
| NS2 | 70 | S453/G21/D1 | G903/S2 | S61 | S |
1
Avian and human amino acid signatures in different viral genes of influenza A viruses as previously determined[20]. Numerical superscripts refer to the number of strains that possess those residues.