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. Author manuscript; available in PMC: 2014 Oct 1.
Published in final edited form as: Trends Biochem Sci. 2013 Sep 10;38(10):10.1016/j.tibs.2013.07.004. doi: 10.1016/j.tibs.2013.07.004

Figure 4. LC and ID regions in signaling proteins associated with stress granules.

Figure 4

Proteins are shown to scale, with LC (aqua) and ID (orange) regions indicated. Note that several SG-associated signaling proteins (RACK1, TRAF2) are highly structured and devoid of LC/ID regions; these proteins bind to SG-integral factors (eIF3 and 40S ribosomal subunits) and proteins (eIF4G) that presumably regulates their recruitment to SGs via more canonical binding of rigid domains. Note that some proteins here (DYRK3, OGFOD1) are also SG-nucleating proteins. The numbers to the right of each schematic indicates the number of amino acids in the isoform shown (usually the largest one); numbers in brackets indicate the reference.