Table 1.
Summary of relative expression of RLR and their associated molecules in microglia and astrocytes constitutively (Resting) or following VSV challenge (+VSV)
Microglia | Astrocytes | |||
---|---|---|---|---|
Molecule | Resting | +VSV | Resting | +VSV |
RIG-I | ||||
mRNA | ++ | ++ | + | +++ |
Protein | ++ | +++ | + | ++ |
MDA5 | ||||
mRNA | ++ | +++ | ++ | +++ |
Protein | ++ | ++++ | ++ | +++ |
LGP2 | ||||
mRNA | + | ++ | + | ++ |
Protein | ||||
12 hours | + | ++ | ++ | +++ |
24 hours | + | − | ++ | +++ |
IPS-1 | ||||
mRNA | +++ | + | ++++ | ++ |