Table 2.
Genotype and allele distributions of the IL-16 gene polymorphisms in IS cases and controls.
| IS cases n (%) |
Controls n (%) |
Adjusted OR (95% CI) |
P value | |
|---|---|---|---|---|
| rs4778889 T/C | ||||
| Genotypes | ||||
| TT | 124 (62.6) | 138 (58.5) | 1.00 | |
| TC | 66 (33.3) | 88 (37.3) | 0.56 (0.16–1.98) | 0.36 |
| CC | 8 (4.0) | 10 (4.2) | 0.94 (0.57–1.56) | 0.82 |
| Alleles | ||||
| T | 314 (79.3) | 364 (77.1) | 1.00 | |
| C | 82 (20.7) | 108 (22.9) | 0.93 (0.61–1.40) | 0.72 |
|
| ||||
| rs11556218 T/G | ||||
| Genotypes | ||||
| TT | 88 (44.4) | 136 (57.6) | 1.00 | |
| TG | 102 (51.5) | 94 (39.8) | 1.88 (1.15–3.07) | 0.01 |
| GG | 8 (4.0) | 6 (2.5) | 2.38 (0.63–9.05) | 0.20 |
| Alleles | ||||
| T | 278 (70.2) | 366 (77.5) | 1.00 | |
| G | 118 (29.8) | 106 (22.5) | 1.54 (1.05–2.27) | 0.03 |
|
| ||||
| rs4072111 C/T | ||||
| Genotypes | ||||
| CC | 125 (63.1) | 141 (59.7) | 1.00 | |
| CT | 63 (31.8) | 85 (36.0) | 0.62 (0.37–1.04) | 0.07 |
| TT | 10 (5.1) | 10 (4.2) | 1.38 (0.48–3.97) | 0.55 |
| Alleles | ||||
| C | 313 (79.0) | 367 (77.8) | 1.00 | |
| T | 83 (21.0) | 105 (22.2) | 0.76 (0.49–1.16) | 0.20 |
OR was adjusted for age, gender, hypertension, diabetes mellitus, hypercholesterolemia, and hypertriglyceridemia by binary logistic regression analysis.