Table 1.

Read Anchoring Speed and Accuracy of Pash, BLAT, and BLAST

Program	Reads mapped/minute	Fraction in agreement with BLAST
Pash	235.5	99.2%
BLAT	39.6	99.8%
BLAST	0.6	N/A

Whole-genome shotgun sequencing reads from the chimpanzee genome-sequencing project were independently mapped onto the human genome by Pash, BLAT, and BLAST. BLAST mappings to a single unambiguous location were used as a reference for comparison. Because chimpanzees are closely related to humans, Pash was employed in a high-speed/low-sensitivity mode (see Adjustable Speed/Sensitivity Tradeoff for details).

N/A means not applicable.