Table 2a. Ovarian tumours: histologial subtypes and frequency of DICER1 mutations.
| Tumours studied | Samples with mutation/total cases studied (%) |
|---|---|
| Sex cord-stromal tumoursa |
9/28 (32) |
| Sertoli–Leydig cell tumour | 8/15 (53) |
| Juvenile granulosa cell tumour | 0/4 |
| Unclassified sex cord-stromal tumour | 1/7 (14) |
| Leydig cell tumour | 0/1 |
| Sex cord-stromal tumour with annular tubules |
0/1 |
| Germ cell tumoursb |
3/99 (3) |
| Teratoma—mature | 0/5 |
| Teratoma—immature | 0/15 |
| Yolk sac tumour | 0/20 |
| Embryonal carcinoma | 0/1 |
| Mixed malignant germ cell tumour | 2/14 (17) |
| Dyserminoma/gonadoblastoma | 1/5 (20) |
| Dysgerminoma |
0/39 |
| Miscellaneousc |
0/8 |
| Embryonal rhabdomyosarcoma | 0/1 |
| Small-cell carcinoma of the ovary, hypercalcaemic type |
0/7 |
| Total | 12/135 (9) |
a
Ages 7 months to 66 years (median age 16 years).
b
Ages birth to 39 years (median age 17 years).
c
Ages 15 to 46 years (median 18 years).