Table 4.
Non-lipid coronary heart disease risk factor changes during the 12-week study
| Intervention | Week 1 1 | Week 12 | P-value 2 | P-value 3 | Change 4 | P-value 5 | |
|---|---|---|---|---|---|---|---|
| Systolic BP (mm Hg) |
ADF |
124 ± 4 |
117 ± 4 |
0.02 |
0.85 |
-7 ± 2 |
0.51 |
| |
Control |
119 ± 3 |
120 ± 4 |
0.67 |
|
1 ± 3 |
|
| Diastolic BP (mm Hg) |
ADF |
78 ± 3 |
72 ± 2 |
0.03 |
0.05 |
-6 ± 2 |
0.17 |
| |
Control |
82 ± 4 |
84 ± 5 |
0.28 |
|
2 ± 6 |
|
| Homocysteine (umol/dl) |
ADF |
9 ± 1 |
9 ± 1 |
0.37 |
0.50 |
0 ± 1 |
0.21 |
| |
Control |
9 ± 1 |
9 ± 1 |
0.86 |
|
0 ± 1 |
|
| C-reactive protein (mg/L) |
ADF |
2 ± 1 |
1 ± 1 |
0.29 |
0.01 |
-1 ± 1 |
0.01 |
| |
Control |
1 ± 1 |
1 ± 1 |
0.78 |
|
0 ± 1 |
|
| Adiponectin (ng/ml) |
ADF |
10728 ± 1251 |
11401 ± 1197 |
0.58 |
0.15 |
672 ± 1191 |
<0.01 |
| |
Control |
11350 ± 1369 |
10509 ± 1316 |
0.26 |
|
-842 ± 623 |
|
| Leptin (ng/ml) |
ADF |
25 ± 4 |
15 ± 3 |
0.04 |
0.55 |
-10 ± 3 |
0.03 |
| |
Control |
22 ± 7 |
18 ± 6 |
0.07 |
|
-4 ± 3 |
|
| Resistin (ng/ml) |
ADF |
18 ± 3 |
15 ± 4 |
0.15 |
0.57 |
-3 ± 3 |
0.20 |
| Control | 23 ± 4 | 21 ± 4 | 0.26 | -2 ± 2 |
Values reported as mean ± SEM. ADF: Alternate day fasting.
1Baseline values were not significantly different between intervention groups for any parameter: Independent samples t-test.
2P-value between week 1 and week 12: Paired t-test.
3P-value between groups at week 12: Independent samples t-test.
4Absolute change between week 1 and week 12 values.
5P-value between groups for absolute change: Independent samples t-test.