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. 2013 Oct 31;2013:297537. doi: 10.1155/2013/297537

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Copyright © 2013 Margaret E. Morrison et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Bim^−/− pericytes diminished capillary morphogenesis of retinal endothelial cells. Wild-type (WT) and Bim^−/− retinal endothelial cells (REC) were plated alone or with wild-type or Bim^−/− pericytes (PC) in Matrigel and photographed in digital format (panel (a)). The quantitative assessment of the data is shown in panels (b) and (c). In panel (d), wild-type retinal endothelial cells were plated alone or with Bim^−/− pericytes in the presence or absence of sFlt1 or IgG control (10 μg/mL) and photographed. Panel (e) is the quantitative assessment of the data in panel (d). The data are the mean number of branch points per field (×40) ± SD. These experiments were repeated at least twice with similar results (***P < 0.001; ****P < 0.0001).