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. 2013 Dec 1;140(23):4672–4682. doi: 10.1242/dev.093286

Fig. 2.

Fig. 2.

magoo mutant cortex has reduced production of progenitors. (A) Pax6 (green) and Tbr2 (red) mark apical and basal progenitors, respectively, in control and magoo mutant cortical sections. Scale bars: 20 μm for each age pair. (B) The number of Tbr2+ progenitors per 100 μm length of ventricle is significantly reduced in magoo mutants at E14.5 and E16.5 compared with controls. Number of brains for +/+ and -/-: E14.5 and E16.5, 3 and 3, n=6 fields each; E18.5, 2 and 2, n=4 fields each. (C) The average thickness of the vz (Pax6+) is slightly reduced in E14.5 and increased in E16.5 mutants. Number of brains for +/+ and -/-: E14.5 and E16.5, 3 and 3, n=6 fields each; E18.5, 2 and 2, n=4 fields each. (D) The vz makes up a larger proportion of the total cortical thickness in magoo mutant cortices at E14.5 and E16.5. Number of brains for +/+ and -/-: E14.5, 3 and 3, n=5 and n=6 fields, respectively; E16.5, 3 and 3, n=4 and n=6 fields, respectively; E18.5, 2 and 2, n=4 fields each. *P<0.05, **P<0.01, ***P<0.001.