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DAC-2-25 and derivatives for SAR studies. A subset of the 44 derivatives of DAC-2-25 (I) that were used for SAR studies is shown. Those that are not shown in the figure are listed in supplementary material Appendix S1. Compounds II, III, V, VII and IX did not induce ectopic tentacles. Compounds IV, VI, VIII, X and XI induced ectopic tentacles.
