Table 3.
sCD23 (units/mL) | sCD27 (units/mL) | sCD30 (units/mL) | CXCL13 (pg/mL) | IL6 (pg/mL) | CRP (μg/mL) | |
---|---|---|---|---|---|---|
|
||||||
Baseline characteristics | ||||||
WIHS site | ||||||
New York | 49 | 494 | 115 | 213 | 2.7 | 3.3 |
DC | 56 | 361 | 103 | 220 | 1.5 | 1.5 |
California | 39 | 342 | 76 | 153 | 1.2 | 2.0 |
Chicago | 64 | 406 | 78 | 198 | 2.0 | 2.3 |
p-value | 0.338 | 0.075 | 0.052 | 0.230 | 0.044 | 0.470 |
Race/ethnicity | ||||||
African-American, non- Hispanic | 47 | 409 | 92 | 211 | 2.0 | 2.3 |
White, non-Hispanic | 52 | 422 | 92 | 173 | 1.4 | 2.7 |
Latina/Hispanic | 54 | 339 | 76 | 113 | 1.3 | 2.0 |
p-value | 0.877 | 0.557 | 0.698 | 0.018 | 0.372 | 0.872 |
Education | ||||||
Less than high school | 59 | 420 | 97 | 197 | 1.7 | 1.7 |
High school graduate | 40 | 409 | 83 | 194 | 1.9 | 3.1 |
More than high school | 49 | 381 | 90 | 175 | 1.7 | 2.6 |
p-value | 0.342 | 0.785 | 0.670 | 0.760 | 0.894 | 0.263 |
HCV positivea | ||||||
No | 49 | 376 | 87 | 177 | 1.7 | 3.0 |
Yes | 49 | 519 | 103 | 233 | 2.1 | 1.0 |
p-value | 0.977 | 0.022 | 0.324 | 0.116 | 0.469 | 0.005 |
Characteristics at AIDS-NHL diagnosis or reference date | ||||||
Reference year | ||||||
1995–2001 | 51 | 425 | 103 | 210 | 2.0 | 2.1 |
2002–2008 | 46 | 366 | 71 | 154 | 1.5 | 2.8 |
p-value | 0.633 | 0.224 | 0.008 | 0.039 | 0.216 | 0.404 |
Age (years) | ||||||
<30 | 35 | 397 | 130 | 241 | 1.8 | 1.9 |
30–39 | 55 | 399 | 94 | 196 | 1.9 | 3.1 |
40–49 | 47 | 433 | 90 | 177 | 1.5 | 1.6 |
≥50 | 31 | 322 | 44 | 141 | 1.7 | 1.8 |
p-value | 0.427 | 0.683 | 0.016 | 0.502 | 0.896 | 0.318 |
Cigarette smokingb | ||||||
Never | 53 | 340 | 79 | 158 | 1.1 | 2.2 |
Current | 51 | 504 | 105 | 208 | 2.2 | 2.1 |
Former | 43 | 336 | 83 | 209 | 2.6 | 3.0 |
p-value | 0.781 | 0.001 | 0.129 | 0.200 | 0.025 | 0.726 |
CD4+ T cells/mm3 c | ||||||
<200 | 44 | 450 | 123 | 243 | 2.6 | 3.0 |
200–400 | 45 | 427 | 95 | 189 | 1.1 | 1.1 |
>400 | 52 | 354 | 65 | 142 | 1.5 | 2.4 |
p-value | 0.731 | 0.171 | <0.001 | 0.002 | 0.019 | 0.065 |
HIV RNA copiesd | ||||||
<4000 | 45 | 299 | 55 | 128 | 1.2 | 2.2 |
4000–20,000 | 43 | 429 | 106 | 200 | 1.4 | 2.1 |
>20000 | 56 | 504 | 126 | 253 | 2.8 | 2.6 |
p-value | 0.544 | <0.001 | <0.001 | <0.001 | 0.005 | 0.837 |
Prior AIDS diagnosis | ||||||
No | 51 | 426 | 94 | 179 | 1.8 | 2.5 |
Yes | 47 | 387 | 87 | 195 | 1.8 | 2.2 |
p-value | 0.710 | 0.434 | 0.570 | 0.560 | 0.945 | 0.682 |
Prior HAART exposureb | ||||||
No | 50 | 447 | 110 | 207 | 2.2 | 2.0 |
Yes | 48 | 366 | 75 | 172 | 1.5 | 2.8 |
p-value | 0.836 | 0.091 | 0.005 | 0.203 | 0.094 | 0.284 |
RNA positive or antibody positive at baseline study visit
“No” indicates unexposed at all three serum sampling time points, “Yes” indicates exposed at least one time point