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. Author manuscript; available in PMC: 2014 Nov 1.
Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2013 Sep 17;22(11):10.1158/1055-9965.EPI-13-0614. doi: 10.1158/1055-9965.EPI-13-0614

Table 3.

Geometric means for immune markers at visit 0–1 year prior to reference date among HIV-infected control women by select characteristics

sCD23 (units/mL) sCD27 (units/mL) sCD30 (units/mL) CXCL13 (pg/mL) IL6 (pg/mL) CRP (μg/mL)

Baseline characteristics
WIHS site
 New York 49 494 115 213 2.7 3.3
 DC 56 361 103 220 1.5 1.5
 California 39 342 76 153 1.2 2.0
 Chicago 64 406 78 198 2.0 2.3
 p-value 0.338 0.075 0.052 0.230 0.044 0.470
Race/ethnicity
 African-American, non- Hispanic 47 409 92 211 2.0 2.3
 White, non-Hispanic 52 422 92 173 1.4 2.7
 Latina/Hispanic 54 339 76 113 1.3 2.0
 p-value 0.877 0.557 0.698 0.018 0.372 0.872
Education
 Less than high school 59 420 97 197 1.7 1.7
 High school graduate 40 409 83 194 1.9 3.1
 More than high school 49 381 90 175 1.7 2.6
 p-value 0.342 0.785 0.670 0.760 0.894 0.263
HCV positivea
 No 49 376 87 177 1.7 3.0
 Yes 49 519 103 233 2.1 1.0
 p-value 0.977 0.022 0.324 0.116 0.469 0.005
Characteristics at AIDS-NHL diagnosis or reference date
Reference year
 1995–2001 51 425 103 210 2.0 2.1
 2002–2008 46 366 71 154 1.5 2.8
 p-value 0.633 0.224 0.008 0.039 0.216 0.404
Age (years)
 <30 35 397 130 241 1.8 1.9
 30–39 55 399 94 196 1.9 3.1
 40–49 47 433 90 177 1.5 1.6
 ≥50 31 322 44 141 1.7 1.8
 p-value 0.427 0.683 0.016 0.502 0.896 0.318
Cigarette smokingb
 Never 53 340 79 158 1.1 2.2
 Current 51 504 105 208 2.2 2.1
 Former 43 336 83 209 2.6 3.0
 p-value 0.781 0.001 0.129 0.200 0.025 0.726
CD4+ T cells/mm3 c
 <200 44 450 123 243 2.6 3.0
 200–400 45 427 95 189 1.1 1.1
 >400 52 354 65 142 1.5 2.4
 p-value 0.731 0.171 <0.001 0.002 0.019 0.065
HIV RNA copiesd
 <4000 45 299 55 128 1.2 2.2
 4000–20,000 43 429 106 200 1.4 2.1
 >20000 56 504 126 253 2.8 2.6
 p-value 0.544 <0.001 <0.001 <0.001 0.005 0.837
Prior AIDS diagnosis
 No 51 426 94 179 1.8 2.5
 Yes 47 387 87 195 1.8 2.2
 p-value 0.710 0.434 0.570 0.560 0.945 0.682
Prior HAART exposureb
 No 50 447 110 207 2.2 2.0
 Yes 48 366 75 172 1.5 2.8
 p-value 0.836 0.091 0.005 0.203 0.094 0.284
a

RNA positive or antibody positive at baseline study visit

b

“No” indicates unexposed at all three serum sampling time points, “Yes” indicates exposed at least one time point