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. Author manuscript; available in PMC: 2014 Nov 11.
Published in final edited form as: Biomacromolecules. 2013 Oct 18;14(11):10.1021/bm401122q. doi: 10.1021/bm401122q

Figure 5. SDF-1α NP exhibits the same chemotactic activity as that of the free form (FF).

Figure 5

(A) Dose-response curves of SDF-1α (circle) and SDF-1α NP (square) in Jurkat cell migration assay. Note that the dose of SDF-1α NP is normalized to SDF-1α content in the NPs. (B) Inhibition assay for Jurkat cell migration: 10 ng/ml SDF-1α or SDF-1α NP was used to induce Jurkat cell migration, which was inhibited by AMD3100. (C) Competition assay for Jurkat cell migration. The assays were carried out by addition of 3 ng/ml SDF-1α (FF) to the bottom wells of the transwell plate, and SDF-1α NPs or control NPs at various concentrations to the top wells. Jurkat cells were loaded in the upper wells.