Figure 3.
FFBF vs. follow-up time of CFRT vs. HFRT RCTs benchmarked to high-dose RT arm of escalation RCTs for prostate cancer.
The y-axis shows the freedom from biochemical failure (FFBF), and the x-axis shows the follow-up time in years. Individual arms of phase III randomized controlled trials (RCTs) comparing conventionally fractionated radiotherapy (CFRT, black squares, ∎) and hypofractionated radiation therapy (HFRT, black triangles, ▴) are shown on the plot with first author and year of publication. As a benchmark for these studies, the higher-dose arms of dose escalation studies (gray circles, ●) are shown on the plot with first author and year of publication. The individual RT schedule of an arm is shown near each data point: total dose, number of fractions, and Gy/fraction.