Fig. 3.
IL-1β induces tau phosphorylation and decreases synaptophysin in cortical neurons. A, Illustrations of phosphorylated tau (Tau-phos) and total tau (Total-tau) in cortical neurons treated with IL-1β (30 ng/ml) for up to 12 hr. B, Synaptophysin (Syn) in cultures treated for up to 12 hr.C, Quantification of protein levels of Syn and Tau-phos in neuronal cultures treated with IL-1β (30 ng/ml) for 2 hr. Values are expressed as mean ± SEM of four samples. *p< 0.05; **p < 0.01.