Table 4.
Association of baseline characteristics with clinical cure or treatment failure among 2188 children with non-severe pneumonia randomised to 3 days or 5 days treatment with amoxicillin: intention to treat analysis. Values are numbers (percentages) of patients unless stated otherwise
| Characteristic | Cure (n=1963) | Treatment failure (n=225) | Odds ratio (95% CI) |
|---|---|---|---|
| Breathing difficulty | 726 (37.0) | 78 (34.7) | 1.1 (0.8 to 1.5) |
| Cough | 1938 (98.7) | 221 (98.2) | 1.4 (0.5 to 4.1) |
| Fever | 1518 (77.3) | 165 (73.3) | 1.2 (0.9 to 1.7) |
| Vomiting | 246 (12.5) | 30 (13.3) | 0.9 (0.6 to 1.4) |
| Age <12 months | 860 (43.8) | 94 (41.8) | 1.1 (0.8 to 1.4) |
| Male | 1220 (62.1) | 141 (62.7) | 1.0 (0.8 to 1.4) |
| Wheeze | 259 (13.2) | 28 (12.4) | 1.1 (0.7 to 1.6) |
| Duration of illness ≤3 days | 959 (48.9) | 119 (52.9) | 0.8 (0.6 to 1.1) |
| Excess respiratory rate <10 breaths/minute | 1627 (82.9) | 157 (49.8) | 2.1 (1.5 to 2.9) |
| Excess respiratory rate <6 breaths/minute | 1183 (60.3) | 108 (48.0) | 1.6 (1.2 to 2.2) |
| RSV positive | 448 (22.8) | 65 (28.9) | 0.7 (0.5 to 0.99) |
| Weight for height z score −3 to −2 | 339 (17.3) | 32 (14.2) | 1.3 (0.9 to 1.9) |
| Adherence to treatment at day 5 | 1818 (92.6) | 47 (20.9) | 47.5 (33.0 to 68.3) |
RSV=respiratory syncytial virus.