Table 1.
Study groups
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Variables | All participants (n=487) | Placebo (n=119) | Acetazolamide group (n=118) | Ginkgo group (n=124) | Combined acetazolamide and ginkgo (n=126) |
No (%) male | 337 (69) | 88 (74) | 79 (67) | 83 (67) | 88 (70) |
Mean (SD) age (years) | 36.6 (10.9) | 36.4 (10.8) | 36.4 (11.0) | 36.7 (10.5) | 36.7 (11.4) |
No (%) if trekkers starting from 2800 m* | 395 (81) | 91 (76) | 101 (86) | 104 (84) | 99 (79) |
Mean No (SD) nights to ascend from 2800 m | 4.7 (1.3) | 4.6 (1.2) | 4.7 (1.1) | 4.5 (1.9) | 4.9 (1.5) |
No (%) enrolled at 4358 m† | 259 (53) | 67 (56) | 58 (49) | 68 (55) | 66 (52) |
No (%) with baseline Lake Lousie score of 1‡ | 27 (5) | 6 (5) | 7 (6) | 6 (5) | 8 (6) |
Mean (SD) baseline oxygen saturation | 85.4 (4.3) | 85.9 (4.3) | 85.3 (4.4) | 84.8 (4.8) | 85.5 (3.7) |
No (%) lost to follow up§ | 127 (26) | 32 (27) | 34 (29) | 33 (27) | 28 (22) |
Lukla airport is at about 2800 m, and trekkers starting from Jiri (2000 m) pass through Lukla.
Enrolment occurred in villages of Dingboche (4358 m) and Pheriche (4280 m).
Most participants at baseline scored zero.
From original 614 participants.