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. Author manuscript; available in PMC: 2014 Sep 1.
Published in final edited form as: Dev Biol. 2013 Jun 17;381(1):10.1016/j.ydbio.2013.06.010. doi: 10.1016/j.ydbio.2013.06.010

Figure 2. FN is not required for cardiac chamber specification.

Figure 2

A–D. Expression of ANF mRNA in control (A, C) and FN-null (B, D) hearts. ANF is expressed in the atria, the left ventricle and to a limited extent, in the right ventricle. The expression patterns of ANF in control and FN-null embryos are comparable. Long arrow in A points to the proximal OFT, and short arrow – to the distal. E. Cited 1 mRNA is confined to the left ventricle in control embryos. Inset in E shows the right side view. F. Expression of Cited 1 mRNA in FN-null heart is limited to the lower region of the straight heart tube, the presumptive left ventricle. E9.5 embryos are shown. A- atria, other abbreviations are as in Fig. 1. Scale bars in all figures are 100 μm unless otherwise stated.