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. Author manuscript; available in PMC: 2014 Aug 1.
Published in final edited form as: Front Neuroendocrinol. 2013 Jul 17;34(3):10.1016/j.yfrne.2013.07.003. doi: 10.1016/j.yfrne.2013.07.003

Fig. 10.

Fig. 10

(A and B) Photomicrographs of Fos expression in the MnPO, 90 min after focal microinfusion of either vehicle (A, aCSF) or senktide (B). Note the marked increase in Fos-immunoreactive nuclei in senktide-microinfused rats. (C) Core temperature before and after vehicle or senktide microinfusion into the MnPO of ovariectomized, estradiol-treated rats (ambient temperature of 21.5 °C, mean ± SEM, n = 6–8 microinfusions/group). Senktide microinfusion into the MnPO markedly decreased core temperature. Scale bar in B = 100 microns and applies to A and B. aCSF, artificial cerebrospinal fluid, 3V, Third ventricle; ac, anterior commissure; MnPO, median preoptic nucleus. # Significantly different, senktide compared with vehicle. Modified with permission from Dacks et al. (2011a).