Table 3. Cytogenetic Risk Groups based on the Byrd classification for 3 different endpoints (20).
All Patients N=517 | COG N=281 | CALGB N=149 | SWOG N=87 | ||||||
---|---|---|---|---|---|---|---|---|---|
Risk Group for CR | N | % | N | % | N | % | N | % | p-value |
Favorable | 79 | 27% | 42 | 26% | 27 | 28% | 10 | 32% | 0.889 |
Intermediate | 176 | 62% | 101 | 63% | 54 | 57% | 21 | 68% | 0.459 |
Adverse | 31 | 11% | 17 | 11% | 14 | 15% | 0 | 0% | 0.050 |
Unknown | 231 | 121 | 54 | 56 | |||||
Risk Group for Relapse | |||||||||
Favorable | 79 | 29% | 42 | 28% | 27 | 30% | 10 | 33% | 0.797 |
Intermediate | 156 | 58% | 87 | 57% | 50 | 56% | 19 | 63% | 0.756 |
Adverse | 37 | 14% | 23 | 15% | 13 | 14% | 1 | 3% | 0.225 |
Unknown | 245 | 129 | 59 | 57 | |||||
Risk Group for Overall Survival | |||||||||
Favorable | 80 | 28% | 42 | 26% | 28 | 29% | 10 | 32% | 0.732 |
Intermediate | 141 | 50% | 80 | 50% | 45 | 47% | 16 | 52% | 0.887 |
Adverse | 65 | 22% | 38 | 24% | 22 | 23% | 5 | 16% | 0.646 |
Unknown | 231 | 121 | 54 | 56 |