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. 2013 Nov 19;8(11):e80296. doi: 10.1371/journal.pone.0080296

Figure 5. Case 2. MRI and biomarker profile in a patient with traumatic axonal injury but normal-appearing structural MRI.

Figure 5

Panels a-d) are MRI images at the corpus callosum and fornix level. Panels e-h) are MRI images at the level of superior coronal radiata. Panel i) is blood biomarker profile. FLAIR and SWI images both indicate the skalp contusion at the parieto-occipital region (long arrows) but normal-appearing brain structure. However, both DTI TBSS and VBA analyses detected significantly reduced FA values at the ipsilateral side (corticospinal tract) and contralateral side (superior corona radiata) of brain white matter (arrow heads), in suggestion of coup and contra coup injury at the microstructure of white matter. Cold color indicates reduced FA values in comparison with controls (t>3 for t-test). Blood biomarkers indicate slightly increased GFAP levels over time but significantly increased UCH-L1 at the admission.