Table 1.

Food intake, body weight, and abdominal trunk composition in dogs maintained on a HHFD

Variable	Week 0	Week 2	Week 6	Week 12	Week 16
	Rimonabant group (n = 11)
FI, kcal·kg−1·day−1	80.2±3.7	65.1±4.1a,d	80.6±5.0	73.7±3.2	70.0±3.1
Body wt, kg	31.7±1.3	29.9±1.1c	30.1±1.1c	30.6±1.2a	30.8±1.1b
Abdominal trunk
TT, cm3	3,105.6±145.5	2,953.7±115.9	2,898.9±125.5b	3,056.3±123.4	3,062.6±134.4
NFT, cm3	2,016.0±88.0	2,004.2±75.3e	2,010.0±71.1	2,103.0±82.1	2,126.9±85.5
TF, cm3	1,089.5±118.3	949.5±95.2b	888.9±109.3c	953.3±93.1b	935.6±108.2b
VAT, cm3	611.3±57.9	523.6±41.6	519.7±60.0	574.0±48.7	555.9±63.9
SAT, cm3	478.3±63.5	425.8±59.1	369.2±54.7c	379.3±46.9c	379.7±48.9c
VAT/SAT	1.4±0.1	1.2±0.1	1.5±0.1	1.6±0.1b	1.5±0.1
TF (%) of the TT	34.5±2.4	31.7±2.3	29.9±2.7c	30.8±2.2a	29.9±2.6c
VAT (%) of the TF	57.1±1.4	56.3±1.9	59.2±1.9	61.0±1.3b	59.7±1.4
SAT (%) of the TF	42.9±1.4	43.7±1.9	40.8±1.9	39.0±1.3b	40.3±1.4
	Placebo group (n = 9)
FI, kcal·kg−1·day−1	84.8±4.1	81.2±3.0	83.4±3.6	80.2±5.7	76.3±4.3
Body wt, kg	31.8±1.5	31.8±1.5	32.4±1.5	33.5±1.7c	33.9±1.9c
Abdominal trunk:
TT, cm3	3,113.7±143.4	3,173.4±146.0	3,220.9±161.6	3,371.8±218.7b	3,404.5±207.4b
NFT, cm3	2,233.1±106.8	2,229.2±63.9	2,241.1±91.7	2,283.7±113.2	2282.7±99.2
TF, cm3	880.6±138.2	944.1±138.6	979.8±165.9	1,088.1±202.9a	1,121.8±194.7c
VAT, cm3	506.0±70.3	551.2±76.6	555.9±83.9	624.9±112.4b	641.0±103.8a
SAT, cm3	374.6±74.8	393.0±70.5	423.9±88.3	463.2±95.9a	480.8±97.5c
VAT/SAT	1.5±0.2	1.3±0.2	1.4±0.2	1.4±0.1	1.4±0.1
TF (%) of the TT	27.7±3.2	28.9±2.8	29.5±3.3	30.9±3.6a	31.7±3.4c
VAT (%) of the TF	58.6±2.8	58.9±2.8	57.8±2.6	57.8±2.3	57.8±2.6
SAT (%) of the TF	41.4±2.8	41.1±2.8	42.2±2.6	42.2±2.3	42.2±2.6

Values are means ± SE. FI, food intake; HHFD, hypercaloric high-fat diet; NFT, nonfat tissue; SAT, subcutaneous adipose tissue; TF, total fat; TT, total tissue; VAT, visceral adipose tissue.

^aP < 0.01,

^bP < 0.05, and

^cP < 0.001 compared with week 0.

^dP < 0.01 and

^eP < 0.05 compared with placebo.