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. 2013 Nov 19;8(11):e80004. doi: 10.1371/journal.pone.0080004

Table 1. Silk fibroin scaffold groups information for in vivo module.

Experimental Group 1 (EG 1) Experimental Group 2 (EG 2) Experimental Group 3 (EG 3) Experimental Group 4 (EG 4) Control Group (CG)
Layer 1 Mulberry silk Mulberry silk + TGF-β Non-Mulberry silk Non-Mulberry silk + TGF-β Empty defect
Layer 2 Mulberry silk Mulberry silk + BMP-2 Non-Mulberry silk Non-Mulberry silk + BMP-2 Empty defect
Layer 3 Mulberry silk Mulberry silk + BMP-2 Non-Mulberry silk Non-Mulberry silk + BMP-2 Empty defect

Different combination of layered scaffold with/without growth factors was used to repair osteochondral defects in rat patella femoral grooves.