Table 1. Silk fibroin scaffold groups information for in vivo module.
Experimental Group 1 (EG 1) | Experimental Group 2 (EG 2) | Experimental Group 3 (EG 3) | Experimental Group 4 (EG 4) | Control Group (CG) | |
Layer 1 | Mulberry silk | Mulberry silk + TGF-β | Non-Mulberry silk | Non-Mulberry silk + TGF-β | Empty defect |
Layer 2 | Mulberry silk | Mulberry silk + BMP-2 | Non-Mulberry silk | Non-Mulberry silk + BMP-2 | Empty defect |
Layer 3 | Mulberry silk | Mulberry silk + BMP-2 | Non-Mulberry silk | Non-Mulberry silk + BMP-2 | Empty defect |
Different combination of layered scaffold with/without growth factors was used to repair osteochondral defects in rat patella femoral grooves.