Table 1. Silk fibroin scaffold groups information for in vivo module.

	Experimental Group 1 (EG 1)	Experimental Group 2 (EG 2)	Experimental Group 3 (EG 3)	Experimental Group 4 (EG 4)	Control Group (CG)
Layer 1	Mulberry silk	Mulberry silk + TGF-β	Non-Mulberry silk	Non-Mulberry silk + TGF-β	Empty defect
Layer 2	Mulberry silk	Mulberry silk + BMP-2	Non-Mulberry silk	Non-Mulberry silk + BMP-2	Empty defect
Layer 3	Mulberry silk	Mulberry silk + BMP-2	Non-Mulberry silk	Non-Mulberry silk + BMP-2	Empty defect

Different combination of layered scaffold with/without growth factors was used to repair osteochondral defects in rat patella femoral grooves.