Table 3.

Differences in Symptom SEVERITY Ratings Across the Four Older Age Groups

Symptom	60 to <65	65 to <70	70 to <75	≥75	Ordinal Age Four Levels
	Mean (SD)	Mean (SD)	Mean (SD)	Mean (SD)	OR	CI
Pain	2.2 (0.8)	2.0 (0.9)	2.1 (0.9)	2.3 (0.8)	1.09	0.87, 1.38
Lack of energy	2.3 (1.0)	2.1 (0.7)	2.1 (0.9)	2.1 (0.8)	0.86	0.68, 1.09
Feeling drowsy	1.8 (0.7)	1.9 (0.7)	1.8 (0.7)	1.7 (0.7)	0.89	0.69, 1.17
Difficulty sleeping	2.1 (0.8)	2.3 (0.7)	2.2 (0.7)	2.2 (0.7)	1.07	0.80, 1.43
Difficulty concentrating	1.8 (0.9)	1.5 (0.7)	1.4 (0.6)	1.8 (0.5)	1.01	0.73, 1.41
Worrying	1.9 (0.9)	1.6 (0.6)	1.9 (0.7)	1.7 (0.9)	0.90	0.64, 1.28
Dry mouth	1.9 (0.9)	1.8 (0.9)	1.9 (0.9)	1.9 (0.9)	1.04	0.78, 1.40
Sweats	2.0 (0.7)	1.8 (0.8)	1.9 (0.9)	1.7 (0.6)	0.76	0.54, 1.08
Constipation	2.0 (1.0)	2.2 (0.8)	2.4 (1.1)	2.2 (0.8)	1.11	0.81, 1.52
Feeling irritable	1.8 (0.6)	1.5 (0.6)	1.8 (0.8)	1.6 (0.6)	0.91	0.63, 1.29
Numbness/tingling in hands/feet	2.0 (0.8)	2.0 (1.0)	1.8 (0.9)	1.7 (0.8)	0.79	0.57, 1.10
Problems with urination	2.0 (0.8)	1.9 (0.9)	2.1 (0.8)	2.1 (0.8)	1.19	0.86, 1.65
Feeling sad	1.9 (1.0)	1.4 (0.5)	1.7 (0.6)	1.7 (0.8)	1.03	0.72, 1.48
Cough	1.9 (0.9)	1.7 (0.8)	1.7 (0.8)	1.8 (0.7)	0.97	0.71, 1.33
Changes in the way food tastes	2.0 (0.8)	1.9 (0.8)	2.1 (0.9)	1.8 (0.9)	0.89	0.63, 1.26
Problems with sexual interest	2.8 (1.3)	2.7 (1.0)	2.9 (1.0)	2.0 (1.3)	0.81	0.50, 1.31
Shortness of breath	2.0 (1.0)	2.1 (0.9)	1.9 (0.8)	1.9 (1.0)	0.91	0.64, 1.29
Changes in skin	2.0 (1.0)	1.8 (0.7)	1.7 (1.1)	1.9 (0.8)	0.90	0.59, 1.38
Nausea	2.2 (0.9)	1.6 (0.7)	1.6 (0.8)	2.0 (0.8)	.85	0.59, 1.24
I don’t look like myself	2.1 (0.9)	1.4 (0.6)	1.9 (0.8)	1.9 (0.9)	0.91	0.61, 1.36
Feeling nervous	1.8 (1.1)	1.7 (0.7)	1.8 (0.6)	1.8 (0.9)	1.14	0.77, 1.71
Weight loss	1.6 (0.9)	1.4 (0.5)	1.8 (0.9)	1.8 (0.7)	1.38	0.89, 2.14
Lack of appetite	2.0 (0.8)	2.0 (0.8)	2.1 (0.9)	1.9 (0.8)	0.93	0.65, 1.32
Feeling bloated	2.1 (1.0)	1.9 (0.7)	1.6 (0.5)	1.6 (0.7)	0.64	0.39, 1.05
Diarrhea	2.3 (0.9)	1.7 (0.7)	1.4 (0.5)	1.9 (0.6)	0.72	0.46, 1.10
Hair loss	2.2 (1.3)	2.4 (1.1)	1.8 (0.9)	2.9 (1.2)	1.32	0.81, 2.14
Dizziness	1.3 (0.5)	1.5 (0.7)	1.4 (0.5)	1.6 (0.8)	1.17	0.76, 1.83
Itching	2.2 (1.2)	1.8 (0.8)	1.5 (0.6)	1.8 (0.8)	0.84	0.54, 1.31
Difficulty swallowing	2.3 (0.7)	1.7 (0.9)	1.8 (0.6)	1.4 (0.7)	0.48 a	0.27, 0.84
Mouth sores	1.8 (1.2)	1.6 (0.9)	1.6 (0.8)	1.5 (0.7)	0.93	0.51, 1.70
Vomiting	2.0 (0.5)	1.6 (0.7)	1.5 (0.6)	1.9 (0.9)	0.88	0.49, 1.58
Swelling of arms or legs	2.0 (0.6)	2.1 (0.9)	2.0 (0.9)	2.1 (0.9)	1.01	0.61, 1.67

SD = standard deviation; OR = odds ratio; CI = confidence interval.

Severity ratings: 1= slight, 2 = moderate, 3 = severe, 4 = very severe for patients who reported the occurrence of a symptom.

^aP <0.05.