Results are shown as the mean ± SEM for traits. Significant differences (P<0.05) are bold. SBP indicates systolic blood pressure; DBP, diastolic blood pressure; SVC/SV Compliance, systemic vascular compliance; BRS up, baroreceptor slope upward deflection, BRS down, baroreceptor slop downward deflection; pEPI, plasma epinephrine; CHGB, chomogranin B; pFFA, plasma free fatty acids; eGFR (CKD-EPI), estimated glomerular filtration rate by Chronic Kidney Disease Epidemiology Collaboration algorithm; pRenin, plasma active renin.
(a) Heritability (h2) of hemodynamic, autonomic, and metabolic traits.
(b) Genetic pleiotropy for plasma norepinephrine (pNE) with correlated traits, plotting RhoG (genetic covariance) as a function of RhoE (environmental covariance). The diagonal line is the theoretical line of identity (Y = X).