Fig. 8.

Cysteamine-induced duodenal ulcers in Sprague-Dawley rats and in heterozygous (+/b) and homozygous (b/b) Belgrade rats. A: light microscopy of duodenal ulcers in rats treated with cysteamine (25 mg/100 g) in Sprague-Dawley rats (deep ulcer, left), heterozygous (deep ulcer, middle), and homozygous Belgrade rats (small ulcer, right) (hematoxylin and eosin staining). B: duodenal ulcer crater dimensions in the same groups of rats were measured in millimeters, and the ulcer areas were calculated using the ellipsoid formula. Size of duodenal ulcers is shown as mm² (means ± SE, *P < 0.01).