Figure 3.

Combined effect of CA and anticancer drugs on the proliferation of ovarian carcinoma cells. Ovarian carcinoma cells, (A) SKOV3, (B) RMG-1 and (C) ES-2, were incubated with 10 μM anticancer drugs, PTX, CDDP and DOX, concurrently with or without 20 μM CA for 24 h. Cell viability was then determined using a WST-8 assay (as described in Materials and methods). Data are presented as the mean ± SD. ^*P<0.01 vs. the control. CA, corosolic acid; PTX, paclitaxel; CDDP, cisplatin; DOX: doxorubicin.