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Chronic cocaine or haloperidol does not induce CREB in MSN subtypes. A, Immunostaining for CREB and GFP in striatum of D2-GFP mice after chronic cocaine or chronic haloperidol (Fig. 1 and 2 legends for drug treatments). Scale bar, 50 μm. B, C, Cocaine or haloperidol does not significantly induce CREB protein levels in D1-MSNs or D2-MSNs.
