Similarly oriented mid-sagittal sections of embryonic heads and surface renderings (viewed from the side, top and front) of the cerebral ventricles at five gestational stages: (a) E10.5; (b) E11.5; (c) E12.5; (d) E13.5; (e) E14.5. Anatomic axes are indicated as anterior-posterior (A-P), dorsal-ventral (D-V) and right-left (R-L). Labels: AQ, aqueduct; BA, basilar artery; cervical flexure, CF; choroid plexus, CP; IT, isthmus; lv, lateral ventricle; MF, mesencephalic flexure; PF, pontine flexure; SS, superior sagittal sinus; SV, spinal vein; VA, vertebral artery; VV, vitelline vessels; 3v, third ventricle; 4v, fourth ventricle. Yellow arrows (a–d) indicate a cross section of the CP in the lateral ventricles; red arrows (d) indicate facial blood vessels. Dashed lines show the MF, PF and CF flexure angles. Scale bars (e) = 1-mm.