Table 3. Cone density and arrangement in eyes with retinitis pigmentosa vs. normal eyes.
Eyes with RP (14 eyes of 14 patients) | Normal eyes (12 eyes of 12 volunteers) | P * | ||
Age (y) | 42.64±12.46 | 38.17±6.84 | 0.211 | |
logMAR VA | −0.11±0.07 | −0.17±0.06 | 0.538 | |
0.5 mm | Cone density (cones/mm2) | 16,200±3,683 | 22,237±1,900 | <0.001 |
Ratio of hexagonal Voronoi domain (%) | 39.9±3.1 | 44.2±2.9 | 0.002 | |
Average NND/expected NND | 0.67±0.03 | 0.72±0.02 | <0.001 | |
1.0 mm | Cone density (cones/mm2) | 13,376±2,840 | 15,975±1,040 | 0.021 |
Ratio of hexagonal Voronoi domain (%) | 40.4±3.4 | 46.8±4.9 | 0.002 | |
Average NND/expected NND | 0.66±0.04 | 0.73±0.02 | <0.001 |
Mann-Whitney U test.
VA: visual acuity, NND: nearest-neighbor distance, RP: retinitis pigmentosa.