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. 2013 Nov 19;8(11):e79447. doi: 10.1371/journal.pone.0079447

Table 3. Cone density and arrangement in eyes with retinitis pigmentosa vs. normal eyes.

Eyes with RP (14 eyes of 14 patients) Normal eyes (12 eyes of 12 volunteers) P *
Age (y) 42.64±12.46 38.17±6.84 0.211
logMAR VA −0.11±0.07 −0.17±0.06 0.538
0.5 mm Cone density (cones/mm2) 16,200±3,683 22,237±1,900 <0.001
Ratio of hexagonal Voronoi domain (%) 39.9±3.1 44.2±2.9 0.002
Average NND/expected NND 0.67±0.03 0.72±0.02 <0.001
1.0 mm Cone density (cones/mm2) 13,376±2,840 15,975±1,040 0.021
Ratio of hexagonal Voronoi domain (%) 40.4±3.4 46.8±4.9 0.002
Average NND/expected NND 0.66±0.04 0.73±0.02 <0.001
*

Mann-Whitney U test.

VA: visual acuity, NND: nearest-neighbor distance, RP: retinitis pigmentosa.