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. 2013 Dec;84(6):854–864. doi: 10.1124/mol.113.087833

TABLE 1.

Radioligand binding assay in D2R and D3R

Statistical significance was determined by one-way analysis of variance with the Bonferroni post-hoc test.

Compound D2R D3R D2R/D3R
pKi S.E.M. pKi S.E.M. Ki/Ki Ratio
NAPS 9.47 0.04 9.26 0.06 0.6
R-22a 6.82 0.01 9.02 0.07 157.2
C3 7.07 0.04 7.31 0.06 1.7
C4a 7.24 0.01 8.90 0.06 45.7
C5a 7.48 0.09 8.42 0.06 8.8
a

pKi values at D2R and D3R for a given compound are significantly different (P < 0.05).